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ANTIBODY STIMULATION IN INDIVIDUALS WITHOUT DEMONSTRABLE POLIOVIRUS ANTIBODIES FOLLOWING A FIFTH INJECTION OF INACTIVATED POLIOVIRUS VACCINE
Author(s) -
Böttiger Margareta
Publication year - 1973
Publication title -
acta pathologica microbiologica scandinavica section b microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-5563
DOI - 10.1111/j.1699-0463.1973.tb02279.x
Subject(s) - poliovirus , inactivated poliovirus vaccine , booster dose , virology , antibody , immunization , medicine , poliomyelitis , antibody response , immunology , stimulation , virus
The effect of a fifth dose of inactivated poliovirus vaccine was estimated in a group of recruits, belonging to the age groups comprising the individuals in Sweden who received the first, less effective poliovirus vaccines. As a rule they had received their primary immunization (3 shots) during the years 1957–59 and a fourth injection around 1963 to 64. The response to the fifth dose given in 1971 indicated that they responded well to the antibody stimulus.Even individuals without demonstrable antibodies prior to the booster reacted to a high degree with an antibody rise similar to that of a secondary response.