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INFLUENCE OF SERUM ON THE BACTERICIDAL ACTIVITY OF NEUTROPHIL GRANULOCYTES
Author(s) -
Solberg Claus O.,
Hellum Kjell B.
Publication year - 1973
Publication title -
acta pathologica microbiologica scandinavica section b microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-5563
DOI - 10.1111/j.1699-0463.1973.tb02252.x
Subject(s) - intracellular , granulocyte , microbiology and biotechnology , in vitro , bacteria , phagocytosis , neutrophile , chemistry , intracellular parasite , immunology , biology , biochemistry , genetics
The influence of serum on the intracellular killing of bacteria by neutrophil granulocytes has been examined using a method which facilitates a precise in vitro evaluation of the phagocytic and bactericidal activities of polymorphonuclear leucocytes. In the absence of serum, a marked reduction in intracellular killing of bacteria was observed. Serum markedly enhances the bactericidal activity of neutrophil granulocytes.