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AMINE‐HANDLING PROPERTIES OF APUD‐CELLS IN THE BRONCHIAL EPITHELIUM OF HUMAN FOETUSES AND IN THE EPITHELIUM OF THE MAIN BRONCHI OF HUMAN ADULTS
Author(s) -
Hage Esther
Publication year - 1973
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1973.tb00477.x
Subject(s) - amine gas treating , epithelium , chemistry , cell , respiratory epithelium , pathology , microbiology and biotechnology , biochemistry , biology , medicine , organic chemistry
In bronchial epithelium of human foetuses, cells containing fluorogenic amine were observed to take up amine precursors and to synthesize and store further amounts of amine. Other cells apparently devoid of a cellular store of amine were capable of taking up amine precursors. The possibility of distinguishing two cell types is discussed. In human adults, no aminecontaining cells were observed in the epithelium of the main bronchi. However, a few cells with a specific fluorescence were obtained after treatment with the precursor amino acid L‐DOPA.