Premium
RETICULUM CELL NEOPLASMS IN NORMAL AND BENZENE TREATED HAIRLESS MICE
Author(s) -
Lerum Ole Didrik
Publication year - 1973
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1973.tb00476.x
Subject(s) - hairless , reticulum , endoplasmic reticulum , benzene , cell , reticulum cell sarcoma , pathology , biology , medicine , endocrinology , chemistry , microbiology and biotechnology , biochemistry , organic chemistry
The occurrence of reticulum cell neoplasms in normal and benzene treated hairless mice (hr/hr) was investigated. 39 per cent of a group of untreated mice had these neoplasms at a mean age of about 20 months. The same tumour yield was also found in another group of mice which were painted twice weekly on the back skin with benzene up to a mean age of 20 months. The histological patterns of reticulum cell neoplasms characteristic of these mice are described.