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CYTOGENETICAL FINDINGS IN CHILDREN BORN TO CARRIERS OF HEPATITIS‐ASSOCIATED ANTIGEN
Author(s) -
Mikkelsen Margareta,
Skinhøj Peter,
Olesen Henrik
Publication year - 1973
Publication title -
acta pathologica microbiologica scandinavica section b microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-5563
DOI - 10.1111/j.1699-0463.1973.tb00213.x
Subject(s) - cord blood , antigen , hepatitis , cord , pregnancy , immunology , biology , medicine , virology , andrology , genetics , surgery
The chromosomes of 50 newborn infants, born to healthy HAA carriers were examined. No chromosomal syndrome was observed. As compared with a control group, the number of amodal cells was found to be significantly higher and the relative proportion of stable aberrations was also higher in the HAA group. Furthermore, cells with rings and dicentrics were found and the number of culture failures was significantly higher. These findings suggest that infection with the HAA agent has occurred early in pregnancy even though HAA could not be detected in cord blood.