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THE ANTIBACTERICIDAL EFFECT OF RABBIT ANTISERUM ON THE KILLING OF A SMOOTH STRAIN OF SALMONELLA ENTERITIDIS BY CATTLE NORMAL SERUM
Author(s) -
Normann Bengt,
Schenström Ola,
Edebo Lars
Publication year - 1973
Publication title -
acta pathologica microbiologica scandinavica section b microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-5563
DOI - 10.1111/j.1699-0463.1973.tb00212.x
Subject(s) - antiserum , salmonella enteritidis , rabbit (cipher) , strain (injury) , salmonella , microbiology and biotechnology , immunoelectrophoresis , sephadex , antibody , biology , chemistry , virulence , immunology , bacteria , biochemistry , enzyme , anatomy , statistics , genetics , mathematics , gene
Rabbit serum, that is hyperimmune to a smooth, virulent strain of Salmonella enteritidis inhibits the bactericidal effect of normal cattle serum on the strain. After fractionation on DEAE‐cellulose such activity was demonstrated in the IgG‐antibody fraction. If further purified on Sephadex G‐25 and tested in immunoelectrophoresis with anti‐whole rabbit serum, the antibactericidal fraction, gave a single precipitation arc, identical with the line developed with specific anti‐rabbit IgG serum.