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IMMUNOLOGICAL FACTORS AND HIGH BLOOD PRESSURE IN MAN
Author(s) -
Olsen Finn
Publication year - 1972
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1972.tb02173.x
Subject(s) - medicine , antibody , blood pressure , disease , immune system , gastroenterology , immunology
Twelve patients suffering from systemic hypertension without symptoms of collagen disease or other types of systematic disease with the exception of arterial hypertension were examined with a view to concentrations of serum immunoglobulins. One patient showed a percentage increment of the immunoglobulins and five patients showed absolute increments of the serum immunoglobulins. Two patients showed raised levels of IgA, one patient of IgG, one of IgM and one patient of both IgG, IgA and IgM. Biopsies were obtained from the kidney, the liver, the skeletal muscles and the skin of the latter patient but any signs suggestive of a collagen disease were not found. The raised values of the serum immunoglobulins occured in patients in whom the systemic hypertension was of short duration, estimated on the basis of the subjective symptoms, and the patients were people in whom the arterial hypertension was new‐discovered. It is discussed whether the raised levels of serum immunoglobulins in hypertensive patients are an index of the hypertensive damage of the blood vessels or whether some cases of systematic hypertension are auto immune diseases.