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ON THE SPECIFICITY OF THE G ABNORMALITY IN HUMAN MENINGOMAS STUDIED BY THE FLUORESCENCE TECHNIQUE
Author(s) -
Mark Joachim,
Mitelman Felix,
Levan Göran
Publication year - 1972
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1972.tb00352.x
Subject(s) - fluorescence , abnormality , pathology , biology , microbiology and biotechnology , chemistry , medicine , physics , optics , psychiatry
The chromosomes were studied in eight human meningomas using the fluorescence technique. Five tumours had a hypodiploid stemline with the loss of 1 No. 22, two tumours had a pseudodiploid stemline with a structurally changed G22, and one tumour had a normal stemline but contained variant cells with the loss of one G22. The results were in accordance with previous preliminary observations and demonstrated that there was a specific G pattern in the human meningomas. This G pattern was compared with that found in chronic myeloic leukaemia in man, and the similarities were proposed to be due to basic progressional mechanisms.