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PROSTATIC WEIGHT IN ELDERLY MEN
Author(s) -
Haugen Olav A.,
Harbitz Thorstein B.
Publication year - 1972
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1972.tb00348.x
Subject(s) - autopsy , medicine , prostate , hyperplasia , diabetes mellitus , carcinoma , body weight , urology , pathology , endocrinology , cancer
Prostatic weight was analysed in a consecutive autopsy series of 172 men over 40 years of age among whom none had clinically manifest carcinoma of the prostate or had previously been subjected to prostatic surgery. The weight of the prostate increased with age only in glands showing benign nodular hyperplasia (BNH). Carcinoma often occurred in small glands (less than 20 grams), and carcinomatous glands generally had lower weight than glands with BNH alone. Prostatic weight showed a positive and significant correlation to body weight. Patients dying from cardiovascular disease and patients with clinically manifest diabetes mellitus had higher prostatic weight than others. Multiple regression analysis showed a significant correlation between prostatic weight and age. On the other hand, a strong correlation between age and BNH existed. Thus, when age was not included in the analysis, it was shown that of the factors tested in the present series, the presence of BNH, body weight, death from cardiovascular disease, and diabetes mellitus were of significance for prostatic weight variability, although the total effect of these factors was relatively low. It may be advisable to correct for these factors in analyses of prostatic weight in an autopsy material.