Premium
THE SENSITIVITY OF THE SKIN OF HAIRLESS MICE TO THE TUMORIGENIC ACTION OF COAL TAR IN RELATION TO THE TETRAZOLIUM TEST
Author(s) -
Iversen Ulla,
Iversen Olav Hilmar
Publication year - 1972
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1972.tb00323.x
Subject(s) - hairless , coal tar , carcinogen , chemistry , tar (computing) , coal , coke , toxicology , biology , biochemistry , organic chemistry , computer science , programming language
A 1 per cent solution of crude coal tar from the Norwegian Coke Factory was tested with the tetrazolium test for carcinogenicity. The result was, as expected, positive. The carcinogenic potency of this tar in long term paintings on hairless mouse skin confirmed the well known carcinogenicity of coal tar, but revealed also that this particular strain of hairless mice is rather sensitive to chemical carcinogens.