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HISTOLOGICAL TYPING OF GASTRIC CARCINOMA
Author(s) -
Stalsberg Helge
Publication year - 1972
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1972.tb00311.x
Subject(s) - autopsy , medicine , pathology , surgical pathology , histology , metastatic carcinoma , carcinoma
Histological classification of gastric carcinomas into the main types intestinal and diffuse was made according to Laurén's method. Autopsy material was compared to surgical material, and metastases were compared to primary tumours, with regard to type distribution and reproducibility. The proportion of diffuse tumours was substantially higher in the total autopsy material than in the total surgical material. This was probably due to a stronger tendency for diffuse tumours to reach an inoperable stage before the diagnosis is made. In patients from whom both surgical and autopsy specimens were available, the same type was diagnosed in both in the majority of cases, and the proportion of diffuse tumours was only slightly higher if typed from the autopsy material than if typed from the surgical material. The reproducibility of histological typing in two independent readings of the same sections was 91 per cent in surgical material and 84 per cent in autopsy material. Metastases reproduced the histological type of the primary tumour in 65 per cent for all metastatic sites combined. Diffuse patterns were most frequently reproduced in metastases to adipose and fibrous tissues, and intestinal patterns were most frequently reproduced in metastases to the liver.