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ELECTRONMICROSCOPICAL STUDY OF MUSCLE BIOPSIES FROM HEALTHY YOUNG PEOPLE Methodology and Results
Author(s) -
ReskeNielsen Edith,
Harmsen Aage
Publication year - 1972
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1972.tb00304.x
Subject(s) - biopsy , human muscle , muscle biopsy , voluntariness , pathology , anatomy , medicine , skeletal muscle , philosophy , epistemology
Electronmicroscopy has been performed on biopsy material from human striated muscle—obtained on the basis of voluntariness and good‐will of eleven young, healthy students. The results are presented in this paper, which deals with the following two main subjects: 1. Information concerning the technical procedures used in this laboratory with remarks on certain important points at different stages in the preparation. 2. The results of an extensive electronmicroscopical investigation of these biopsies which revealed a rather pronounced morphological variation in young, healthy, human subjects. The classic electron‐microscopic morphology of striated muscle has in reality for many years been based on animal experiments. This investigation in healthy human subjects has demonstrated a morphology basically identical to that of animal muscle, but it seems as if additional elements must be regarded as necessary parts of a true electronmicroscopic picture of striated muscle in man.

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