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MARGINAL VACUOLES IN FINE NEEDLE ASPIRATION BIOPSY SMEARS OF TOXIC GOITERS
Author(s) -
Nilsson Göran
Publication year - 1972
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1972.tb00282.x
Subject(s) - vacuole , biopsy , pathology , thyroid , marginal zone , cytoplasm , chemistry , medicine , antibody , immunology , biochemistry , b cell
A special type of vacuoles, called marginal vacuoles, and occurring in the cytoplasm of the follicular epithelium cells in smears from fine needle aspiration biopsy specimens is described. Marginal vacuoles were found to be much more frequent in toxic than in atoxic goiters. The difference was so clear that it was considered to be of some value in the examination of biopsy smears from the thyroid. It is suggested that markedly dilated cisterns of the endo‐plasmatic reticulum are the most likely ultrastructural counterparts of the vacuoles.