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ON MILD DEGREES OF FLUOROSIS
Author(s) -
Sundström B.
Publication year - 1972
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1972.tb00264.x
Subject(s) - resorption , depigmentation , dentistry , distilled water , enamel paint , medicine , chemistry , dermatology , chromatography
24 recently weaned Sprague‐Dawley rats were divided equally into 3 groups and given distilled drinking water ad libitum containing 0, 1 or 5 ppm F‐ (as NaF), respectively. Among the 13 animals that received the fluoridated water and survived the 2‐year experimental period, 4 developed macroradiographically demonstrable resorption cavities in their femurs. Three of these animals belonged to the 1 ppm group. No resorption cavities were seen in the 6 surviving, control rats. There was no sign of tooth changes, especially no striated depigmentation of the enamel of the incisors.