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Primary Hyperparathyroidism In a case of Oxyphilic Adenoma
Author(s) -
Heimann Peter,
Hansson Göran,
Nilssonl Oiov
Publication year - 1971
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1971.tb00506.x
Subject(s) - medicine , primary hyperparathyroidism , adenoma , pathology , parathyroid adenoma , hyperparathyroidism , surgery
A 47‐year‐old man with clinical manifestations of hyperparathyroidism was shown to have a parathyroid adenoma which in light‐microscopy chiefly consists of oxyphilic cells and transitional forms of chief cells and oxyphilic cells. Electron‐microscopy shows that the oxyphilic cells contain tightly packed mitochondria and that the transitory cells are rich in mitochondria. In these latter cells there are signs of stimulated protein synthesis. It is probable that these cells produce the excess of parathyroid hormone. Oxyphilic cells would seem to be developed from the chief cells.