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CHEMICAL ANALYSIS OF A SALIVARY GLYCOPROTEIN WITH BLOOD‐GROUP SUBSTANCE‐AND VIRUS INHIBITION ACTIVITIES
Author(s) -
Sønju Torleif,
Rølla Gunnar
Publication year - 1971
Publication title -
acta pathologica microbiologica scandinavica section b microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-5563
DOI - 10.1111/j.1699-0463.1971.tb00038.x
Subject(s) - glycoprotein , fucose , abo blood group system , saliva , biochemistry , amino acid , chemistry , microbiology and biotechnology , biology , immunology
A human salivary glycoprotein which exhibits blood‐group substance activity in the ABO and Lewis systems, and which also inhibits the haemagglutinins of influenza virus ( Rølla &Jonsen 1968) has been analysed. Glycoprotein preparations from a non‐secretor (O, Le a+b ‐ ) and from a secretor (O, Le a ‐ b+) showed very similar amino acid composition, indicating identical protein cores in the two glycoproteins, whereas the secretor preparation contained more amino sugars and fucose. The salivary blood‐group active glycoproteins had an amino acid composition different from the ovarian cyst blood‐group substances and contained more protein than these preparations.