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VARIATION IN STAPHYLOCOCCAL PROTEIN A REACTIVITY WITH γG‐GLOBULINS OF DIFFERENT SPECIES
Author(s) -
Lind Inga,
Live Israel,
Mansa Bendt
Publication year - 1970
Publication title -
acta pathologica microbiologica scandinavica section b microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-5563
DOI - 10.1111/j.1699-0463.1970.tb04357.x
Subject(s) - globulin , antibody , gamma globulin , biology , staining , titer , chemistry , absorption (acoustics) , microbiology and biotechnology , biochemistry , immunology , genetics , physics , acoustics
The reactivity between protein A of S. aureus and serum globulins from various species was found to vary. Sera from three species (man, dog and swine) gave high titre for non‐specific staining in the fluorescent antibody test (FAT), formed distinct precipitation lines with protein A and absorption with Cowan type I removed all γG‐globulin components to such a degree that only traces were left. Sera from two other species (cow and sheep) showed a less marked or weak reaction in FAT, did not readily precipitate protein A and by absorption with Cowan type I the slow γG‐globulin component was completely removed, whereas the fast γG‐globulin seemed to be unaltered.