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GEL PRECIPITATION REACTIONS BETWEEN MEASLES ANTIGENS AND SERA OF PATIENTS WITH MULTIPLE SCLEROSIS
Author(s) -
PANELIUS M.,
SALMI A.,
HALONEN P.
Publication year - 1970
Publication title -
acta pathologica microbiologica scandinavica section b microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-5563
DOI - 10.1111/j.1699-0463.1970.tb04345.x
Subject(s) - subacute sclerosing panencephalitis , measles , antigen , multiple sclerosis , precipitation , measles virus , immunology , virology , medicine , chemistry , vaccination , physics , meteorology
The gel precipitation reactions between measles antigens and serum specimens of 49 patients with multiple sclerosis and 49 age‐matched controls were studied. At least one gel precipitation line was obtained in 76 per cent of the control sera and in 94 per cent of the patient sera (p < 0.01). Five patient sera produced four or five strong precipitation lines against measles antigens, but no lines against the noninfected control antigens. In the serum specimens of the control group not more than three faint precipitation lines against measles antigens were detected. Comparison of the gel precipitation reactions between the sera of these five patients with multiple sclerosis and of a patient with subacute sclerosing panencephalitis indicated an almost identical gel precipitation pattern.