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THYROID EOSINOPHILS AND CUTANEOUS ARTHUS REACTION SIMULTANEOUSLY INDUCED IN THE GUINEA‐PIG BY ANTISERUM TO THYROGLOBULIN
Author(s) -
KÅRESEN ROLF
Publication year - 1970
Publication title -
acta pathologica microbiologica scandinavica section b microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-5563
DOI - 10.1111/j.1699-0463.1970.tb04325.x
Subject(s) - thyroglobulin , guinea pig , thyroid , eosinophil , antiserum , immunology , medicine , skin reaction , peripheral blood mononuclear cell , granulocyte , arthus reaction , pathology , antigen , endocrinology , asthma , chemistry , biochemistry , in vitro
Guinea‐pigs injected with guinea‐pig thyroglobulin intradermally and rabbit antiserum to guinea‐pig thyroglobulin intravenously, showed inflammatory reactions both in the thyroid and in the skin. However, while the eosinophil granulocyte was the predominating cell of the inflammatory infiltrate in the thyroid, neutrophil granulocytes and mononuclear cells prevailed in the skin. Indirect evidence suggested that the reason for this difference might be the larger number of mast cells in the thyroid.