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The validity of biochemical markers in metabolic bone disease in preterm infants: a systematic review
Author(s) -
Visser Fenna,
Sprij Arwen J,
Brus Frank
Publication year - 2012
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.2012.02626.x
Subject(s) - medicine , metabolic bone disease , disease , urinary system , physiology , pediatrics , osteoporosis
To establish the validity of biochemical markers of metabolic bone disease (MBD) in preterm infants. Conclusion: There is insufficient evidence that any of the frequently used serum measurements are valid biochemical markers of MBD in preterm infants. Increased urinary calcium concentration may be a valid biochemical marker, but more research is necessary to confirm this.