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The effect of olfactory stimulation on energy expenditure in growing preterm infants
Author(s) -
Marom Ronella,
ShedliskerKening Tamar,
Mimouni Francis B.,
Lubetzky Ronit,
Dollberg Shaul,
Berger Irit,
Mandel Dror
Publication year - 2012
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.2011.02399.x
Subject(s) - medicine , vanillin , crossover study , gestational age , randomization , resting energy expenditure , anesthesia , randomized controlled trial , incubator , zoology , energy expenditure , physiology , food science , pregnancy , placebo , biology , genetics , alternative medicine , pathology , microbiology and biotechnology
Aim: To test the hypothesis that olfactory stimulation in growing healthy preterm infants leads to an increase in resting energy expenditure (REE). Design: A prospective, randomized clinical trial with crossover was conducted in 20 healthy, appropriate weights for gestational age, gavage‐fed preterm infants. Infants were studied while asleep and cared for in a skin servo‐controlled convective incubator. Using a pipette, 15 drops of saturated solution of vanillin (Aldrich, Fallavier, France) were dripped to a cloth diaper that was placed on the opposite side of the incubator. REE was measured by indirect calorimetry (DeltaTrac II, Helsinki, Finland) exactly 1 h after feeding. Each infant was studied twice by randomization: after a period of 20 min of vanillin odour or after 20 min without vanillin odour. Results: We found no statistically significant difference in REE of preterm infants when exposed to vanillin odour (74.5 ± 10.1 kcal/kg/day) in comparison with their REE when not exposed to vanillin odour (79.0 ± 11.3 kcal/kg/day). Conclusions: Vanillin odour does not significantly influence REE in metabolically and thermally stable preterm infants.