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Effects of parenteral soybean oil lipid emulsion on the long‐chain polyunsaturated fatty acid profile in very‐low‐birth‐weight infants
Author(s) -
Shoji Hiromichi,
Hisata Ken,
Suzuki Mitsuyoshi,
Yoshikawa Naomi,
Suganuma Hiroki,
Ohkawa Natsuki,
Shimizu Toshiaki
Publication year - 2011
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.2011.02183.x
Subject(s) - medicine , polyunsaturated fatty acid , soybean oil , parenteral nutrition , emulsion , lipid emulsion , fat emulsion , food science , fatty acid , biochemistry , pathology , chemistry
Aim: Conventional soybean lipid emulsions contain no docosahexaenoic acid (DHA) or arachidonic acid (AA). We investigated the relationship between blood DHA and AA status in 27 very‐low‐birth‐weight (VLBW) infants with or without parenteral lipid emulsion. Methods: Sixteen infants received parenteral lipid emulsion, and 11 infants were control group. The fatty acid composition of the erythrocyte membrane was analysed at birth and at 2 weeks of age. Results: No significant difference in AA levels was observed in the lipid emulsion group between the two time points, whereas the AA levels at 2 weeks were significantly lower than at birth in the control group. The DHA levels in both groups at 2 weeks were significantly lower than at birth, but no group differences were observed at both time points. Conclusion: The use of parenteral soybean oil lipid emulsions in VLBW infants in the postnatal period may prevent the decline in the AA level but does not appear to influence the DHA level.