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Clinico‐pathological spectrum of gallbladder disease in children
Author(s) -
Punia RPS,
Garg Shailja,
Bisht Bhumika,
Dalal Usha,
Mohan Harsh
Publication year - 2010
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.2010.01876.x
Subject(s) - medicine , pathological , gallbladder , gallbladder disease , disease , pathology , gastroenterology
Aim: Because of wide variation in clinico‐pathological spectrum of gallbladder disease in children the world over, the data of gallbladder disease from this stone belt of India were analysed. Methods: Children who underwent cholecystectomy over a period of 8 years January 2002–December 2009 were reviewed. Results: Out of 7076 cholecystectomies, 56 (0.79%) were in children. Thirty‐nine (69.6%) children were 11–16 years of age. Thirty‐seven (66.07%) children were girls and nineteen (33.9%) were boys. In 12 (21.4%) children, cholecystitis was acalculus. Five (8.9%) children had associated haemolytic disease and 4 (7.1%) children had congenital anomaly in the form of choledochal cyst. Ultrasound findings were available in 44 cases and showed cholelithiasis in 36 cases. Twenty‐two (39.3%) children had mixed cholelithiasis, 8 (14.2%) pigment cholelithiasis, 10 (17.8%) combined cholelithiasis and 4 (7.1%) patients had small concretions. Microscopically, changes of chronic cholecystitis were seen in 98.2% while 1.7% showed acute on chronic cholecystitis. There was single unusual case of cysticercus in the wall of the gallbladder. Conclusions: The frequency of gallstone disease is 0.79%. Nonhaemolytic type of cholelithiasis is more common than haemolytic type in this region. Presence of cysticercus in the gallbladder wall in one case was an unexpected finding.