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Neonatal renal vein thrombosis and prothrombotic risk
Author(s) -
Harris SL,
Smith MP,
Laurie A,
Darlow BA
Publication year - 2010
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.2010.01717.x
Subject(s) - medicine , thrombophilia , thrombosis , factor v leiden , deep vein , venous thrombosis , antithrombin , risk factor , intensive care medicine , pediatrics , heparin
A case of extensive deep venous thrombosis in a four a day old infant was presented. Unusually this patient was shown to be heterozygous for three thrombophilia genes; Factor V Leiden, prothrombin and antithrombin gene mutations, the latter being novel. Conclusion: There are no randomized controlled trials to guide management in deep venous thrombosis in the newborn but knowledge of the prothrombotic risk factors may help direct treatment.