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Cow's milk allergic children can present sensitisation to probiotics
Author(s) -
Bruni Francesca M,
Piacentini Giorgio L,
Peroni Diego G,
Bodini Alessandro,
Fasoli Erica,
Boner Attilio L.
Publication year - 2009
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.2008.01064.x
Subject(s) - medicine , milk allergy , atopic dermatitis , cow's milk allergy , allergy , cow milk , sensitization , probiotic , food allergy , dermatology , food science , immunology , biology , genetics , bacteria
Aim: To evaluate sensitivity to different probiotics in children with cow's milk allergy. Methods: Eighty‐five patients (age range: 4 months –12 years) presenting atopic dermatitis (AD) were enrolled. Skin prick test (SPT) responses to three different probiotics preparations (Fiorilac®, Dicoflor® and Reuterin®) were evaluated in addition to relevant food allergens. Results: Thirty‐nine patients out of 85 (45.8%) had a positive skin response to prick test for cow's milk (3 with reaction <3 mm). Of the thirty‐six patients with a cow's milk weal reaction >3 mm, twenty‐eight (77.8%) had a skin response to Fiorilac®, four patients (11%) to Dicoflor® and four (11%) to Reuterin®. The proportion of SPT reaction to all the investigated probiotics preparations was significantly lower than cow's milk (r = 9.406; p = 0.002). A significantly higher sensitization was observed for Fiorilac® versus Dicoflor® (r = 30.916; p < 0.001) and versus Reuterin® (r = 34.133; p < 0.001). Conclusion: Probiotic use in patients with cow's milk allergy has to be limited to products that do not contain milk. This should be clearly reported in the label. In selected patients, it is advisable to perform a screening SPT with the product to evaluate its potential contamination with milk.