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Development and growth in very preterm infants in relation to NIDCAP in a Dutch NICU: two years of follow‐up
Author(s) -
Wielenga JM,
Smit BJ,
Merkus MP,
Wolf MJ,
Van Sonderen L,
Kok JH
Publication year - 2009
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.2008.01038.x
Subject(s) - bayley scales of infant development , medicine , pediatrics , gestational age , neonatal intensive care unit , prospective cohort study , cohort , cohort study , psychomotor learning , pregnancy , cognition , genetics , psychiatry , biology
Aim: To study development and growth in relation to newborn individualized developmental and assessment program (NIDCAP®) for infants born with a gestational age of less than 30 weeks. Methods: Developmental outcome of surviving infants, 25 in the NIDCAP group and 24 in the conventional care group, in a prospective phase‐lag cohort study performed in a Dutch level III neonatal intensive care unit (NICU) was compared. Main outcome measure was the Bayley scales of infant development‐II (BSID‐II) at 24 months corrected age. Secondary outcomes were neurobehavioral and developmental outcome and growth at term, 6, 12 and 24 months. Results: Accounting for group differences and known outcome predictors no significant differences were seen between both care groups in BSID‐II at 24 months. At term age NIDCAP infants scored statistically significant lower on neurobehavioral competence; motor system (median [IQR] 4.8 [2.9–5.0] vs. 5.2 [4.3–5.7], p = 0.021) and autonomic stability (median [IQR] 5.7 [4.8–6.7] vs. 7.0 [6.0–7.7], p = 0.001). No differences were seen in other developmental outcomes. After adjustment for background differences, growth parameters were comparable between groups during the first 24 months of life. Conclusion: At present, the strength of conclusions to be drawn about the effect of NIDCAP on developmental outcome or growth at 24 months of age is restricted. Further studies employing standardized assessment approaches including choice of measurement instruments and time points are needed.