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A comparison of high and standard blood transfusion volumes in premature infants
Author(s) -
Wong Hubert,
Connelly Robert,
Day Andrew,
Flavin Michael P
Publication year - 2005
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.2005.tb01949.x
Subject(s) - medicine , blood volume , volume (thermodynamics) , blood transfusion , adverse effect , anesthesia , randomized controlled trial , pediatrics , surgery , quantum mechanics , physics
We compared high volume (20 ml/kg) with standard volume (15 ml/kg) packed red blood cell (PRBC) transfusions in a randomized trial. Ten high volume babies received a mean of 2.8 transfusions, while 10 standard volume babies received a mean of 3.4 ( p =0.58). No adverse events were attributed to the use of the high volume transfusions. Conclusion: Higher transfusion volumes appear to be well tolerated. The data can be used in the planning of larger controlled trials in VLBW infants.