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Topographic localization of electrocortical activation in newborn and two‐ to four‐month‐old infants in response to head‐up tilting
Author(s) -
Grieve Philip G,
Myers Michael M,
Stark Raymond I,
Housman Sarah,
Fifer William P
Publication year - 2005
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.2005.tb01850.x
Subject(s) - medicine , electroencephalography , tilt (camera) , audiology , head (geology) , mechanical engineering , geomorphology , psychiatry , engineering , geology
Aims: (1) To confirm that head‐up tilting causes sustained increases in the heart rate (HR) of newborn infants but not during the period of maximum vulnerability to SIDS at 2–4 mo of age, and (2) to determine whether electrocortical activation (changes in high‐frequency EEG power) also shows topographic and age‐dependent effects of tilting. Methods: HR and electrocortical activity were recorded in 15 newborn and 12 2‐ to 4‐mo‐old infants during head‐up tilting. Infants were tilted, three times, to a 30° head‐up position. Electrocortical activity was acquired using a 128‐lead EEG system. Changes in HR and high‐frequency (12–50 Hz) power in the electrocortical signal were computed from the flat to the head‐up position. Results: Newborn infants had significant increases in HR and robust increases in high‐frequency power in the left frontal, right frontal‐temporal, and occipital regions following head‐up tilt. At 2 to 4 mo of age, HR did not change significantly and tilt‐related increases in high‐frequency power were smaller. Conclusion: The patterns of HR change and electrocortical activation with tilting of newborn infants are different from infants at the age of highest risk for SIDS.