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Effect of BCG vaccine on tuberculin skin tests in 7–11‐year‐old children
Author(s) -
Bozaykut A,
Atay E,
Sevim H,
Atay Z,
Ceran O
Publication year - 2004
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.2004.tb02713.x
Subject(s) - medicine , tuberculin , scars , vaccination , skin test , tuberculin test , dermatology , bcg vaccine , tuberculosis , surgery , immunology , pathology
Aim : To determine the effect of Bacillus Calmette Guerin (BCG) vaccination on tuberculin skin test responses in 7–11‐year‐old children, and also to clarify whether the number of vaccinations and the time interval between vaccination and tuberculin skin test have an effect on the test responses. Method : 1200 primary school children were evaluated for the presence and number of BCG scars. They were then given 5 TU PPD‐S intra‐dermally. Seventy‐two hours after the application of tests, PPD indurations were measured. Results : Mean indurations were 3.7 ± 3.9, 6.5 ± 5.4 and 9.2 ± 7.1 mm in children with no scar, one scar and two scars, respectively. No statistical difference was found between mean induration of children with one scar and those with two scars. Conclusion : The effect of the number of BCG vaccinations and the time interval between vaccination and tuberculin skin test application on tuberculin skin test responses was statistically insignificant.