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Corticosteroid treatment in meconium aspiration syndrome: a solution for better outcome?
Author(s) -
Kääpä P
Publication year - 2004
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.2004.tb00664.x
Subject(s) - medicine , meconium aspiration syndrome , corticosteroid , meconium , extracorporeal membrane oxygenation , lung function , dosing , anesthesia , lung , pediatrics , intensive care medicine , pregnancy , surgery , fetus , genetics , biology
Corticosteroid treatment in severe meconium aspiration syndrome may afford, especially if started early, some improvement in oxygenation, lung function and pulmonary haemodynamics during the acute phase of the disorder. Still, the effects of corticosteroids on lung tissue perturbations and outcome of diseased infants remain unclear. Conclusion : Further research is needed to determine the clinical significance and optimal timing and dosing of corticosteroid treatment in severe meconium aspiration syndrome.