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Influence of dietary intervention on growth in children with hypercholesterolaemia
Author(s) -
SánchezBayle M,
SorianoGuillén L
Publication year - 2003
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.2003.tb02574.x
Subject(s) - medicine , cholesterol , ldl cholesterol , endocrinology , apolipoprotein b , outpatient clinic , total cholesterol
Aim : To determine whether a moderately reduced fat diet affects longitudinal growth in children with hypercholesterolaemia with a mean duration of 7.42 ± 1.93 y. Methods : Subjects with hypercholesterolaemia, total cholesterol above 5.18 mmol/L and LDL‐cholesterol above 3.49 mmol/L ( n = 144; 69 males and 75 females) from 2 to 13 y of age were studied. Patients were seen in our outpatient department for regular health check‐ups. Weight and height were measured every year. At the same time, cholesterol, triglycerides, LDL‐C, HDL‐C, A‐apoprotein and B‐apoprotein levels were analysed. Furthermore, degrees of compliance at 1 mo, 6 mo and each year after starting the dietary treatment were determined. Results : No significant change in height or weight was found after fat restriction. In contrast, significant reductions in total cholesterol, LDL cholesterol and B‐apoprotein levels of 19%, 24% and 14%, respectively, were detected. Finally, no significant differences were seen in HDL‐cholesterol, A‐apoprotein or triglycerides. Conclusions : These data support the hypothesis that growth is not influenced by moderate fat restriction in healthy children who otherwise have normal nutrition.