Premium
Characteristic profile of intestinal microflora in Kawasaki disease
Author(s) -
Takeshita S,
Kobayashi I,
Kawamura Y,
Tokutomi T,
Sekine I
Publication year - 2002
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.2002.tb03327.x
Subject(s) - medicine , kawasaki disease , feces , incidence (geometry) , disease , lactobacillus , gastroenterology , immunology , microbiology and biotechnology , bacteria , biology , physics , genetics , optics , artery
To investigate whether the ecology of the intestinal microflora may change in the acute phase of Kawasaki disease (KD), the distribution pattern was studied of common micro‐organisms in feces from 20 patients with KD, 20 patients with acute febrile diseases (disease control) and 20 healthy children. KD patients had a significantly lower ( p > 0.001) incidence of Lactobacillus (2/20, 10%) than disease control patients (16/20, 80%) and healthy children (14/20,70%). KD patients had no significant incidences of other microbial genera, compared with both disease control and healthy children. Conclusion : The results suggest that a lack or loss of the beneficial Lactobacillus genus in the enteric microflora may occur during the acute phase of KD.