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Brain damage markers in children. Neurobiological and clinical aspects
Author(s) -
Leviton A,
Dammann O
Publication year - 2002
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.2002.tb01630.x
Subject(s) - medicine , brain damage , peripheral blood , lesion , pathology , human brain , neuroscience , immunology , biology , psychiatry
The presence in blood of proteins normally confined to the cytoplasm of brain cells is considered peripheral evidence of brain damage. Only recently have these proteins been measured in the blood of children at risk of brain damage. To show the value and limitations of measuring these proteins, we review their biology and the adult literature that has correlated the blood concentrations of these proteins with lesion size and dysfunction. Conclusion : We conclude that brain damage markers will increasingly be measured in the blood of newborn s and other children at risk of brain damage.