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Is oxidative stress involved in the aetiology of pre‐eclampsia?
Author(s) -
Poston L,
Chappell LC
Publication year - 2001
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.2001.tb01619.x
Subject(s) - medicine , eclampsia , oxidative stress , etiology , incidence (geometry) , pregnancy , disease , antioxidant , vitamin e , obstetrics , biochemistry , chemistry , genetics , physics , optics , biology
Pre‐eclampsia is one of the major indications for elective premature delivery. Several lines of evidence suggest that pre‐eclampsia is associated with a state of oxidative stress, offering hope of prevention by antioxidant supplementation. It was recently shown by the present authors that supplementation with vitamin C and E from early in pregnancy leads to a reduction in the incidence of the disease in “high‐risk” women.