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Non‐Epstein‐Barr virus‐associated T‐cell lymphoma following cardiac transplantation for Barth syndrome
Author(s) -
Ronghe MD,
Foot ABM,
Martin R,
Ashworth M,
Steward CG
Publication year - 2001
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.2001.tb00804.x
Subject(s) - medicine , lymphoma , neutropenia , transplantation , disease , cardiomyopathy , myopathy , myocarditis , virus , epstein–barr virus , immunology , pathology , heart failure , chemotherapy
Barth syndrome is a metabolic disease characterized by infantile cardiomyopathy, neutropenia and organic aciduria. We report disease evolution in one of the first affected boys to undergo successful cardiac transplantation. Conclusion: Although cardiac status stabilized, he developed disabling skeletal myopathy, protracted lymphopenia and‐5 y after transplant‐fatal Epstein Barr (EBV)‐negative T‐cell non‐Hodgkin's lymphoma.