Premium
Vitamin D deficiency in Iranian mothers and their neonates: a pilot study
Author(s) -
Bassir M,
Laborie S,
Lapillonne A,
Claris O,
Chappuis MC,
Salle BL
Publication year - 2001
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.2001.tb00802.x
Subject(s) - medicine , hypovitaminosis , vitamin d and neurology , parathyroid hormone , cord blood , alkaline phosphatase , vitamin d deficiency , reference range , pregnancy , calcifediol , endocrinology , physiology , pediatrics , calcium , biochemistry , enzyme , chemistry , biology , genetics
We conducted a pilot study to assess the prevalence of hypovitaminosis D among Iranian women and their newborns. Blood samples were taken from 50 mothers (age 16–40 yr) and their neonates at term delivery in the largest Tehran hospital. The results showed that 80% of the women had 25‐hydroxyvitamin D (25‐OHD) concentrations of less than 25 nmol/l. Mean maternal plasma calcium and phosphatase alkaline concentrations were in the normal range. The mean maternal serum immunoreactive parathyroid hormone concentration of women with hypovitaminosis D (i.e., 25‐OHD levels < 25 nmol/l) was above normal range and significantly different from that of women without hypovitaminosis D. Conclusion: The mean cord serum 25‐OHD concentration was very low (4.94 ± 9.4 nmol/l) and that of infants of mother with hypovitaminosis D were almost undetectable (1.2 ± 1.2 nmol/l).