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Effectiveness of casein hydrolysate feedings in infants with colic
Author(s) -
Jakobsson I,
Lothe L,
Ley D,
Borschel MW
Publication year - 2000
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.2000.tb01180.x
Subject(s) - crying , medicine , hydrolysate , placebo , casein , whey protein , milk protein , infant formula , population , pediatrics , anesthesia , food science , biochemistry , pathology , psychiatry , chemistry , alternative medicine , environmental health , hydrolysis
This study found that two casein hydrolysate formulas varying in composition were equally effective in managing colicky symptoms associated with protein sensitivity. Both hydrolysate formulas were associated with a significant, comparable reduction in crying duration and intensity from baseline in 15 of 22 infants with complete data. Subsequent challenge data suggest that the population studied were infants experiencing colicky symptoms due to protein sensitivity. A greater proportion of infants showed a positive reaction (≥1.5h of crying/d) to the protein challenges than the placebo challenge, and crying was rated as more intense during whey and milk protein challenges.