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Umbilical artery catheter blood sampling decreases cerebral blood volume and oxygenation in very low birthweight infants
Author(s) -
Roll C,
Hüning B,
Käunicke M,
Krug J,
Horsch S
Publication year - 2000
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.2000.tb00394.x
Subject(s) - medicine , blood volume , anesthesia , blood sampling , oxygenation , blood pressure , umbilical artery , oxygen saturation , middle cerebral artery , pco2 , heart rate , cardiology , gestation , oxygen , pregnancy , ischemia , chemistry , organic chemistry , biology , genetics
The aim of this study was to assess whether blood sampling from umbilical artery catheters reduces cerebral blood volume and cerebral oxygenation in very low birthweight infants. A total of 20 infants, median birthweight 890 g (530‐1500 g), median gestation age 26 + 4 wk (range: 22 + 5 to 30 + 6 wk) were studied from 10min before until 10min after routine blood sampling from umbilical artery catheters placed in the high position. Using near infrared spectroscopy, changes in concentrations of cerebral oxygenated and deoxygenated haemoglobin were measured, and changes in cerebral blood volume and cerebral oxygenation index were calculated. Heart rate, oxygen saturation, transcutaneous PO 2 and PCO 2 were registered continuously. Mean arterial blood pressure was measured before and after sampling. Oxygenated haemoglobin decreased significantly from baseline during blood sampling, whereas deoxygenated haemoglobin did not change significantly. This resulted in a decrease in cerebral blood volume and cerebral oxygenation index. Heart rate increased slightly, but significantly, from baseline. Oxygen saturation, blood pressure, transcutaneous PO 2 and PCO 2 did not change significantly. Conclusion : Blood sampling from umbilical artery catheters induces a significant decrease in cerebral blood volume and cerebral oxygenation.