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Passive immunity against rotavirus in infants
Author(s) -
Hammarström L
Publication year - 1999
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1999.tb01311.x
Subject(s) - passive immunity , rotavirus , immunity , antibody , immunology , medicine , clinical trial , virology , immune system , virus
Passive immunity against a variety of gastrointestinal infections, using orally administered human antibodies, has been tried in a number of clinical trials. Recently, antibodies from other species such as cows and chickens, which have shown efficacy in experimental animal systems, have also been tried in humans. This review summarizes published data on the use of immunoglobulin‐containing preparations for prophylaxis and therapy against rotavirus infections in infants and children, and directions for their future use are suggested.