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Plasma lipids, phospholipid fatty acids and indices of glycaemia in 10‐year‐old children born as small‐for‐gestational‐age or preterm infants
Author(s) -
Decsi T,
Erhardt É,
Márkus A,
Burus I,
Molnár D
Publication year - 1999
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1999.tb00165.x
Subject(s) - medicine , endocrinology , apolipoprotein b , phospholipid , small for gestational age , cholesterol , gestational age , gestation , lipoprotein , fatty acid , insulin , pregnancy , biochemistry , biology , genetics , membrane
Low birthweight has been epidemiologically associated with unfavourable plasma lipid profiles and enhanced risk of cardiovascular morbidity in adulthood. Plasma lipids, lipoprotein cholesterols, apolipoproteins, fatty acid composition of plasma phospholipids and basic indices of glycaemia were investigated in 10‐y‐old children born with similarly low birthweights as small‐for‐gestational‐age (SGA; n = 16) or preterm infants (n = 16). Plasma total cholesterol (4.32 ± 0.57 vs 4.60 ± 0.52, mmol l _1 , mean ± SD, SGA vs preterm subjects), low‐density lipoprotein cholesterol (2.54 ± 0.51 vs 2. 65 ± 0.51) and high‐density lipoprotein cholesterol (1.61 ± 0.25 vs 1.76 ± 0.18) concentrations did not differ between the 2 groups. There was no difference in plasma tri‐acylglycerol, apolipoprotein A‐I and B, insulin and glucose concentrations or phospholipid fatty acid values. There was no correlation between indices of lipid and carbohydrate metabolism. In conclusion, plasma lipid profiles and basic indices of glycaemia are not different in 10‐y‐old children born with similarly low birthweights as SGA or preterm infants. □ Apolipoprotein, cholesterol, insulin, lipoprotein cholesterol, low birthweight, phospholipid fatty acid, 10‐y‐old children