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Disseminated Bacillus Calmette‐Guérin infection in a girl with hyperimmunoglobulin E syndrome
Author(s) -
Pasic S,
Lilic D,
Pejnovic N,
Vojvodic D,
Simic R,
Abinun M
Publication year - 1998
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1998.tb01535.x
Subject(s) - medicine , immunodeficiency , primary immunodeficiency , immunodeficiency syndrome , immunology , complication , tuberculosis , immunopathology , dermatology , pathology , surgery , immune system
Disseminated Bacillus Calmette‐Guérin infection occurs in few well‐defined immunodeficiencies, such as severe combined immunodeficiency, chronic granulomatous disease and paediatric acquired immunodeficiency syndrome. This severe complication of immunization against tuberculosis has been lethal in the majority of children who had primary immunodeficiency. Our patient, a 9‐y‐old girl with hyperimmunoglobulin E syndrome developed disseminated Bacillus Calmette‐Guerin infection in infancy. Patients with hyperimmunoglobulin E syndrome (HIES) are susceptible to serious staphylococcal and fungal infections. Disseminated Bacillus Calmette‐Guerin infection has not previously been reported in this rare immunodeficiency.