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Specific cellular immunity in immunocompetent children with herpes zoster
Author(s) -
Terada K,
Tanaka H,
Kawano S,
Kataoka N
Publication year - 1998
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1998.tb01532.x
Subject(s) - medicine , immunity , cellular immunity , immunology , immunocompetence , humoral immunity , antibody , virus , virology , immune system
We investigated whether specific immunity is low in immunocompetent children with zoster. Specific cellular immunity was found to be significantly lower in 13 otherwise normal children with zoster than it was in 8 matched controls by a lymphoproliferative assay. However, there was no significant difference between them with regard to the antibody response. Therefore, even in the immunocompetent children, decreased specific cellular immunity may play an important role in the mechanism of virus reactivation.