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Changes in Doppler ultrasonography in asphyxiated term infants with hypoxic‐ischaemic encephalopathy
Author(s) -
Ilves P,
Talvik R,
Talvik T
Publication year - 1998
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1998.tb01530.x
Subject(s) - medicine , ultrasonography , encephalopathy , doppler effect , ischaemic stroke , cardiology , radiology , ischemia , physics , astronomy
Cerebral blood flow velocity was assessed by pulsed‐Doppler ultrasonography in 39 asphyxiated and 35 healthy term newborn infants during the first days of life. Asphyxiated infants, investigated at the age of 12 ± 2h, with moderate stage hypoxic‐ischaemic encephalopathy (HIE) (n = 7) had decreased (15.6 ± 3.9cm/s) and infants with severe stage of HIE ( n = 8) increased (26.5 ± 9.6 cm/s) mean cerebral blood flow velocity in medial cerebral artery compared to the control group (20.9 ± 3.7 cm/s). Four out of six infants with severe stage of HIE and mean cerebral blood flow velocity of 3 SD above the mean for normal infants at the age of 12 h died and two developed multicystic encephalopathy during the neonatal period. We conclude that severe post‐hypoxic increase of mean cerebral blood flow velocity at the age of 12 ± 2 h is connected with development of severe stage HIE and poor prognosis.