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Epstein‐Barr virus infection and its role in the expanding spectrum of human diseases
Author(s) -
Okano M
Publication year - 1998
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1998.tb01377.x
Subject(s) - medicine , virology , virus , broad spectrum , immunology , combinatorial chemistry , chemistry
Recent advances of the various laboratory tests to detect Epstein‐Barr virus (EBV) infection have clarified the causative role for a spectrum of EBV‐associated diseases. They include lymphoproliferative disorders (LPD), which occur in immunologically compromised individuals, Hodgkin's disease (HD), chronic active EBV infection (CAEBV), virus‐associated hemophagocytic syndrome (VAHS), certain forms of T cell lymphoma, and some gastric carcinomas, in addition to the classical EBV‐associated diseases such as EBV genome‐positive Burkitt's lymphoma (BL), undifferentiated nasopharyngeal carcinoma (NPC) and infectious mononucleosis (IM). This review intends to introduce the recent progress of studies on EBV infection mainly from the clinical points of view.