Premium
Coma in a premature infant associated with the transdermal absorption of propylene glycol
Author(s) -
Peleg O,
BarOz B,
Arad I
Publication year - 1998
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1998.tb00930.x
Subject(s) - medicine , polyvinyl alcohol , coma (optics) , absorption (acoustics) , anesthesia , organic chemistry , chemistry , physics , acoustics , optics
A case of propylene glycol intoxication in a premature infant is reported. The infant went into a state of coma after treatment for burns with antiseptic dressings. Cessation of the topical treatment resulted in complete recovery. An exceptionally high level of the dressings' solvent, propylene glycol, found in the urinary chromatogram, was believed to be the causative agent. It is suggested that topical preparations containing propylene glycol should not be used in premature infants during the first weeks of life.