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Growth hormone treatment of short children born small for gestational age
Author(s) -
Czernichow P.
Publication year - 1997
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1997.tb18419.x
Subject(s) - medicine , short stature , growth hormone treatment , small for gestational age , growth velocity , growth hormone , gestational age , growth retardation , bone age , hormone , endocrinology , intrauterine growth restriction , pregnancy , gestation , pediatrics , biology , genetics
The administration of growth hormone (GH) for a short period to short children born small for gestational age increases growth velocity. Children receiving 2–3 times the replacement dose gained nearly 2.0 SDS in height over a 3‐year treatment period. This treatment is well tolerated, without significant side‐effects. Further studies of the growth rate following cessation of GH treatment will reveal whether the gain in height is maintained, and whether the final height prediction is improved. □ Growth hormone, intrauterine growth retardation, short stature, bone maturation, metabolism