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Endocrine and nutritional regulation of prenatal growth
Author(s) -
Gluckman PD
Publication year - 1997
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1997.tb18399.x
Subject(s) - endocrine system , fetus , medicine , placenta , endocrinology , insulin , fetal growth , pregnancy , insulin like growth factor , gestation , growth factor , hormone , biology , receptor , genetics
Fetal growth in late gestation is primarily determined by the functional status of the pathways by which nutrients are transferred from the maternal compartment, across the placenta, and taken up by the fetal tissues. Both the maternal and fetal endocrine systems can influence this pathway at several levels, including regulation of placental metabolism. The primary fetal axis involved in the regulation of fetal growth is the glucose—insulin—insulin‐like growth factor I axis. □ Fetus, intrauterine growth retardation, insulin‐like growth factor I, growth hormone