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Soluble CD30 serum antigen in Kawasaki disease
Author(s) -
Vagliasindi C,
Spinozzi F,
Sensi L,
Radicioni M,
RosaMX O De,
Solinas L,
Vaccaro R,
Bertotto A
Publication year - 1997
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1997.tb08897.x
Subject(s) - medicine , kawasaki disease , immune system , peripheral blood mononuclear cell , antigen , immunology , cd30 , glycoprotein , disease , pathology , lymphoma , biology , microbiology and biotechnology , in vitro , biochemistry , artery
4 Very high levels of sCD30, a glycoprotein surface antigen expressed by T lymphocytes and other mononuclear cells of the immune system, were found in serum samples from 10 children with typical Kawasaki disease (KD), but not in blood specimens from a vast cohort of paediatric control subjects. These data strongly support an involvement of CD30+T cells in the immune processes which take place at the level of lymphoid organs during the acute phase of KD.