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Dietary factors influencing levels of food antibodies and antigens in breast milk
Author(s) -
Lovegrove JA,
Morgan JB,
Hampton SM
Publication year - 1996
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1996.tb14151.x
Subject(s) - medicine , breast milk , lactation , food allergy , casein , antibody , pregnancy , antigen , breast feeding , immunoglobulin a , allergy , immunology , immunoglobulin e , milk substitute , food science , immunoglobulin g , biology , biochemistry , pediatrics , genetics
The effect of a milk‐free diet during late pregnancy and lactation, on levels of cows’milk specific antibodies and antigens in breast milk, was examined. Women with an allergic condition (defined as atopic) were randomly allocated to a milk‐free diet ( n = 10) or an unrestricted diet ( n = 12). Twelve non‐atopic women followed an unrestricted diet. A significant reduction ( p < 0.001) in β‐lactoglobulin‐specific immunoglobulin A and α‐casein‐specific immunoglobulin A levels was observed over the first 5 days in all groups. The mean level of β‐lactoglobulin antigens in breast milk from women who adhered strictly to the milk‐free diet was significantly lower than the levels of the atopic group on the unrestricted diet ( p < 0.02). The allergy incidence in the infants born in the atopic diet group was significantly lower compared with that of the atopic group on the unrestricted diet.