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Antiphospholipid antibodies in children
Author(s) -
Kontiainen S,
Miettinen A,
Seppälä I,
Verkasalo M,
Mäenpää J
Publication year - 1996
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1996.tb14098.x
Subject(s) - medicine , antibody , antiphospholipid syndrome , immunology , intensive care medicine
Sera from children ( n = 173) were tested for antiphospholipid antibodies (aPL) using an enzyme immunoassay detecting IgG anti‐cardiolipin antibodies (GPL). Sera from adults ( n = 100) were also tested. GPL were detected more frequently and at higher levels in children than in adults. Eighty‐two percent of the children and 27% of the adults tested positive (≥ 10 GPL Uml ‐1 ) for aPL ( p <0.001). Values of 45 GPLUml ‐1 or higher were detected in about 5% of the children, and 25 GPLUml ‐1 or higher in about 5% of the adults. Normal values should be adjusted accordingly.